Symptoms guide · 2,100+ testing locations nationwide
STD Symptoms in Women and Men
Noticed something and not sure what it is? Most STDs cause no symptoms at all, and the ones that do all look alike. Here’s what to watch for – and the only way to know for sure.
Written by the RSC Health editorial team · Updated September 9, 2026
Quick answer: The most common STD symptoms are unusual discharge, burning when you pee, sores or bumps on the genitals, pain during sex, and itching – but most people with an STD have no symptoms at all. If you had an exposure, get tested: order online or call, go to any of 2,100+ partner labs with no appointment, and see your results in 1–2 business days.
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Symptoms by STD
Pick the one you’re worried about, or test for all of them at once with the 10-Test Panel.
Chlamydia symptoms
Around 70% of women and 50% of men with chlamydia have no symptoms. Watch for: unusual vaginal discharge, burning or pain when you pee.
Gonorrhea symptoms
Most women and many men with gonorrhea have no symptoms. Watch for: increased or unusual vaginal discharge, burning when you pee.
Hepatitis B symptoms
Most adults with a new hepatitis B infection have no symptoms, and long-term infection is usually silent. Watch for: tiredness that won’t lift, nausea, vomiting or loss of appetite.
Hepatitis C symptoms
About 4 in 5 people with hepatitis C have no early symptoms and can carry it for decades without knowing. Watch for: fatigue, nausea or poor appetite.
Herpes symptoms
Most people with genital herpes have no outbreaks or such mild ones they never notice. Watch for: small blisters that break into painful sores on the vulva, vagina, buttocks or thighs, tingling, itching or burning before sores appear.
HIV symptoms
After the first few weeks HIV usually causes no symptoms at all for years. Watch for: fever, sore throat and swollen glands 2–4 weeks after exposure, body rash.
Syphilis symptoms
The first sore is painless and often hidden, so most people never notice it. Watch for: a single painless sore (chancre) on the vulva, vagina, cervix, anus or mouth, weeks later: a non-itchy rash, often on the palms and soles.
Trichomoniasis symptoms
About 70% of people with trich have no symptoms. Watch for: frothy, yellow-green vaginal discharge with a strong smell, itching, burning or redness of the genitals.
Symptoms that several STDs share
- Unusual vaginal discharge (color, amount or smell)
- Burning or pain when you pee
- Pain during sex
- Bleeding between periods or after sex
- Sores, blisters, bumps or a rash on or around the genitals
- Itching or irritation
- Lower belly or pelvic pain
- Discharge from the penis
- Burning or pain when you pee
- Sores, blisters, bumps or a rash on the penis, scrotum or groin
- Itching at the tip of the penis
- Pain or swelling in a testicle
- Rectal pain, discharge or bleeding
- Sore throat after oral sex
Remember: because these overlap so much, no symptom points to one STD. Most people who test have no symptoms, and many who worry about one thing find out it was something else. The 10-Test Panel checks the ten most common infections in one visit; if a symptom is severe, or a sore or rash needs examining, see a clinician as well.
Get tested in three easy steps
Tell us what you’re worried about, or pick the tests yourself. A doctor’s order is included – you don’t need a referral or an appointment.
Your lab order reaches the test center in 2–3 minutes, so you can walk in today – no appointment. Go to the lab you chose during the hours listed. Sign in at the kiosk with your name and date of birth – no ID needed – give a small blood or urine sample, and you’re done in about 5 minutes. No exam, no questions, no waiting room full of people.
Results post to your private account in 1–2 business days. Prefer not to log in or get an email? Call and we’ll read your result to you. If anything needs attention, our care team calls you to walk through treatment – for many infections that’s a prescription; for others the physician arranges an in-person visit or a referral.
More about STD symptoms
What STD symptoms look like
The signs that bring most people to this page are a handful that several infections share: burning or pain when you urinate, discharge from the penis or vagina that looks or smells different, pain during sex, bleeding between periods or after sex, sores, blisters or bumps on or around the genitals, itching, a rash, and pain low in the belly or in a testicle. Oral and anal sex add a sore throat and rectal pain, itching, discharge or bleeding, though infections in the throat and rectum are usually silent.
The pages linked above go through each infection in detail. The short version: chlamydia, gonorrhea and trichomoniasis mostly cause discharge and burning, when they cause anything; herpes causes blisters that break into sores; syphilis causes a single painless sore and, weeks later, a rash; HIV causes a brief flu-like illness in some people and then nothing for years; the hepatitis viruses cause tiredness, nausea, dark urine and yellowing of the skin or eyes, when they cause anything at all.
Why most people have no symptoms
For every one of these infections, the most common experience is no symptom at all. The CDC estimates that most people with chlamydia, gonorrhea in women, trichomoniasis, genital herpes and hepatitis B or C do not know they have it, and HIV can go years without a sign. Infections in the throat and rectum are almost always silent. That is not a reason for comfort: silent infections still cause damage – pelvic inflammatory disease, infertility, liver disease – and still pass to partners. A test is the only way to know. Symptoms do not shorten the time an infection takes to show up on a test, and having none does not mean you are clear.
What else causes the same symptoms
Burning when you urinate is more often a urinary tract infection than an STD. Vaginal discharge, itching and odor are more often bacterial vaginosis or a yeast infection. Bumps on the genitals are often ingrown hairs, folliculitis, skin tags, molluscum or friction, and a single sore can be a cut or a reaction to a product. A rash has dozens of causes. None of this means the symptom is not an STD – it means the symptom cannot tell you, and neither can a photo on the internet. A test tells you whether the infection you are worried about is there; a clinician tells you what a sore or rash is.
When to see a clinician rather than wait for a test
Some symptoms need a clinician, not just a lab. A sore, blister, ulcer or rash should be examined – and, where possible, swabbed – while it is there, because a blood or urine test cannot tell you what a sore is. Severe pelvic or lower-belly pain, pain or swelling in a testicle, a fever with pelvic pain, vision or hearing changes, a severe headache, or yellowing of the skin or eyes need prompt medical care. If you are pregnant, tell your prenatal provider about any symptom or exposure. And if you may have been exposed to HIV in the last 72 hours, go to an urgent care or emergency room today and ask about PEP, which can prevent infection only if it is started in time.
How testing works, and what it cannot tell you
Chlamydia, gonorrhea, trichomoniasis and Mycoplasma genitalium are tested from a urine sample; syphilis, HIV, herpes and the hepatitis viruses from a small blood draw. There is no swab and no exam at our partner labs. Each test looks for one infection, so a negative chlamydia test says nothing about gonorrhea, and a urine test checks the urethra and cervix, not the throat or rectum – tell the care advisor about oral or anal exposure. The 10-Test Panel checks the ten most common infections in one visit; trich and M. gen are separate tests, and there is no blood or urine test for HPV. Every test also has a window period after exposure before it can find the infection; the timing for each is on our When to Get Tested page, or call (866) 872-1888 and a care advisor will tell you which test and which day.
After a positive result
Chlamydia, gonorrhea, syphilis, trichomoniasis and M. gen are cured with antibiotics; hepatitis C is cured with a course of pills; herpes, HIV and hepatitis B are managed with medication that lets most people live entirely normally. A member of our care team calls you, explains the result, and sets up a consultation with a physician. Depending on the infection, care is a prescription sent to your pharmacy, an in-person visit for an injection, or a referral to ongoing care. Partners need to be told and tested, and for some infections a retest a few months later checks for re-infection.
Not sure what to test for? Talk to someone first.
Most people call before they order. Tell a care advisor what happened and when – no judgment, no awkwardness – and they will tell you exactly what makes sense, place the order with you, and pick the lab closest to you. The line is open 24 hours a day.
- Talk to a real person, privately
- Get the right test the first time
- Your lab order is at the test center in 2–3 minutes
Nobody finds out but you.
Nothing goes to your insurance. Nothing comes in the mail. Your visit doesn’t announce why you’re there. Our partner labs collect samples for many different kinds of testing. To other people in the waiting room, you’re simply another person having a routine lab visit. Your results go only to you, in your secure account, and your card statement just says RSC Health.
Not sure what to test for?
Call (866) 872-1888. Our care advisors talk to people in your exact situation every day – no judgment, no awkwardness. They’ll tell you what makes sense based on what happened and when.
Call (866) 872-1888 Get Tested Online
Questions people ask about STD symptoms
What are the first signs of an STD?
For most STDs there are none. When there are, the earliest signs are usually burning when you pee, unusual discharge, or a sore or bump on the genitals – the timing varies from days to months depending on the infection.
How long after sex do STD symptoms appear?
Anywhere from a couple of days to a few months, depending on the infection – and most of the time they never appear at all. If you know when the exposure was, call us and we’ll tell you what to test for and when.
Can I have an STD with no symptoms?
Yes – that’s the normal case. Chlamydia, gonorrhea, trich, herpes, HIV and hepatitis are all usually silent. Testing is the only way to know.
Which test should I get if I have symptoms?
If you’re not sure what you were exposed to, the 10-Test Panel checks the ten most common infections with one blood and one urine sample. If you know, pick the single test. A sore, blister or rash is best examined and swabbed by a clinician while it’s there. Either way, call us if you want help choosing.
Will anyone find out I was tested?
No. We never bill insurance, nothing is mailed, your lab visit doesn’t announce why you’re there (our partner labs collect samples for many kinds of testing, so you’re simply another routine visit), and your card statement just says RSC Health.
Resources
The medical information on this page is drawn from the public-health sources below. It is general information, not a diagnosis – a test and, if needed, a physician consultation are how you get an answer for your situation.
- About Sexually Transmitted Infections (STIs) – Centers for Disease Control and Prevention (CDC)
- Screening Recommendations – CDC Sexually Transmitted Infections Treatment Guidelines, 2021
- Sexually Transmitted Infections – MedlinePlus, U.S. National Library of Medicine
- Sexually transmitted infections (STIs) – World Health Organization (WHO)